Grant Application Guidance and Expectations

Application Process

  • All grant-making activity is managed via a web-based portal, grant management system, and all communications related to the application process must be received electronically via this system.  Eligibility and registration fields must be completed and receive approval before any applicant submission.
  • Application Process – Refer to Application Process for details – After Registration, the application process is essentially a two-step process, involving a Letter of Intent (LOI), and if invited, a Formal Proposal.  In general, the entire process may take 90-120 days for final approval and awarding of a grant.
  • Grant Review cycles- 3 per calendar year. A list of due dates for applications can be found here: Mathers Grant Review Process and Due Dates.
  • Desired Start Dates should be for the current cycle only.
  • One application per cycle per investigator.
  • Development offices coordinating applications should submit a limit of 4 applications per cycle per institution/university.


Budgets and duration

  • Grant duration should be three years.
  • The expectation is that an investigation will be completed within the requested duration of the grant (up to 3 years). If the investigation has not been completed, and there are still funds available, a no-cost extension may be requested. If at the end of the grant term, the aims of the project have not been met, an explanation should be provided to the Foundation. (The primary investigator is urged to consider a proposed modification of the project’s original aims to prevent such a situation from occurring).
  • Preliminary Budgets are required during the LOI phase. A detailed budget justification is not required until the proposal phase. This budget justification should provide detailed costs of investigators’ salaries, laboratory supplies, etc.
  • The Foundation’s grant award is not intended to be utilized for purchasing capital equipment (“bricks-and-mortar”) for the lab and is intended only to support the actual investigation. It is the Foundation’s assumption and expectation that capital equipment must be provided by the research institution or university.
  • Indirect Costs for the proposed project cannot exceed 10%.


Application Guidance

  • The Foundation primarily supports basic science, ideally with potential translational applications.
  • Immunology, microbiome, genomics, structural biology, cellular physiology, neuroscience, etc. are some noteworthy examples of current research support. Plant Biology research and Oceanography related research will not be considered for support.
  • As technology continues to advance, it is apparent that investigations in the area of basic science and translational research may become more and more reliant on collaborative, interdisciplinary projects. It is important to note that any interdisciplinary project proposals may require additional information regarding collaborator(s)’ achievements, and relevant expertise.
  • Feedback for declined LOI Requests will not be provided; LOI’s that have been declined, should not be resubmitted at a later date for consideration.
  • Renewal applications for the same or related research will not be accorded priority consideration. It is strongly advised that any re-application for grant renewal consider a new direction based on prior research, or emphasize some new potential translational aspects, and not merely an extension of previously funded research.
  • Requests for funding previously federally supported research, and/or applications pending federal approval will not be accorded priority consideration.
  • Requests for support of clinical trials or drug discovery will not be approved.
  • Grant Agreements must be signed by an authorized signatory for the University/Institution and countersigned by the Primary Investigator.